Search on: NK TRYPTASE 2 
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Descriptor English:   Granzymes 
Descriptor Spanish:   Granzimas 
Descriptor Portuguese:   Granzimas 
Synonyms English:   Cytotoxic Serine Protease B
Cytotoxic T-Lymphocyte Associated 1 Protein
Cytotoxic T-Lymphocyte Proteinase 1
Fragmentin 2
Granzyme
Granzyme A
Granzyme B
Granzyme C
Granzyme K
Granzyme M
Granzyme-3
Granzyme-Like Protein III
Hanukah Factor
NK-Tryptase-2
Natural Killer Cell Granule Tryptase-2
Cytotoxic T Lymphocyte Associated 1 Protein
Cytotoxic T Lymphocyte Proteinase 1
Granzyme 3
Granzyme Like Protein III
NK Tryptase 2
Natural Killer Cell Granule Tryptase 2  
Tree Number:   D08.811.277.656.300.760.397
D08.811.277.656.959.350.397
Definition English:   A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells. 
Pharmacological Action:   Cytotoxins
 
History Note English:   2007(1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52244 
Unique Identifier:   D053804 

Occurrence in VHL:
 

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